Nattokinase Powder

Premium Nattokinase Powder 20000FU/g – Pharmaceutical Grade Fibrinolytic Enzyme for Cardiovascular Health Formulations

Xi'an Yanxi Biotech Co., Ltd provides pharmaceutical-grade Nattokinase Powder, standardised at 20,000 FU/g, using modern purification methods to remove the traditional natto smell and retain the highest enzyme activity. Our biotech facility, established in 2010, uses proprietary fermentation control technologies and ISO 22000 and HACCP certified production lines to ensure batch-to-batch uniformity. This off-white fine powder (100% via 80 mesh) overcomes key B2B formulation issues such dose accuracy, heat stability at 90℃ for 15 minutes and easy incorporation into cardiovascular support capsules and functional blood health supplements.

What is Nattokinase Powder?

Nattokinase is a powerful fibrinolytic enzyme produced by carefully controlled fermentation of non-GMO soybeans with Bacillus subtilis natto. The purified powder form, compared to raw natto food, overcomes viscosity and odour hurdles that have previously hampered popularity in Western markets.

The molecular mechanism of the enzyme is the direct proteolytic activity against fibrin clots. Keeps fibrinogen levels within the usual range to ensure good blood circulation and assists in preserving the elasticity of blood vessels. This results to a clean label cardiovascular ingredient for formulators with proven stability in dry encapsulation methods.

Our 20000FU/g standard is professional-grade potency for therapeutic dosage methods. The fine powder form provides homogeneous dispersion in capsule formulations and tablet compression compositions without clumping or phase separation.

Technical Specifications​​​​​​​

Core Benefits for B2B Formulations

Promotes Cardiovascular Health

The mechanism of the fibrinolytic enzyme is to digest excess fibrin buildup in blood vessels. This contributes to maintaining normal blood viscosity and appropriate circulation characteristics. In clinical settings, the usual formulation is dosed at 100 to 200 mg daily to provide 2000 to 4000 FU enzyme units.

Summary of Improved Stability

Our unique stabilisation technique maintains enzyme activity at processing temperatures up to 90℃ for 15 minutes. Such thermal tolerance is important to tableting operations and hot melt encapsulation methods. The powder is stable at room temperature when protected from moisture and does not require cold chain logistics.

Benefit of Odor-Free Formula

Traditional natto fermenting generates strong sulphurous chemicals that decrease consumer acceptance. Our approach of purification concentrates enzymatic activity and eliminates volatile organic contaminants. The outcome is a neutral smelling powder that can be used with flavoured soft gels and combination formulae with other botanicals.

Quality Assurance System

Multi-Level Certification Compliance

Yanxi Biotech is operated under ISO 22000 food safety management and HACCP critical control standards. Our facility is certified Kosher and Halal for global religious dietary needs. Every production batch is confirmed for enzymatic activity, microbiological limits and heavy metal contamination by third-party SGS testing.

Raw Material Traceability

We keep full supply chain data from the sourcing of the soybeans to fermentation and extraction. Each batch is also supplied with a Certificate of Analysis (COA) attesting enzyme activity by High-Performance Liquid Chromatography (HPLC), microbiological analysis and screening for pesticide residues. This traceability underpins your regulatory filings in FDA, EFSA and TGA nations.

Stability Testing Procedure

Accelerated stability studies at 40℃/75% RH show <5% activity loss over 24 months. Real time ageing data available on request indicates constant performance in HDPE bottles using desiccant packing techniques.

Application Scenarios

Dietary Supplement Products

The fine Nattokinase powder is mixed into vegetarian capsules of 100-200mg per serving and blends very well. It works well with Coenzyme Q10, omega-3 fatty acids and red yeast rice extract in comprehensive cardiovascular support regimens. The neutral pH profile (4.0-5.0 in 1% solution) is stable in enteric coated delivery systems

Integration of Functional Foods

Heat-stable, it can be included into protein bars, functional beverages and meal replacement powders. The enzyme is shielded by protein or polysaccharide matrices and survives pasteurisation methods. Typical levels of inclusion are 0.1-0.3% (w/w) in finished food items.

Applications in Therapeutic Research

Pharmaceutical researchers use our high purity powder for pharmacokinetic investigations and in clinical trial formulations. Standardised potency of 20000FU/g assures reproducibility of dosage in multi-center trials. Small scale research amounts from 1kg with full analytical support are available from us.

Packaging & Shipping

We provide versatile packaging options to suit your production scale. Standard packaging is a 1kg foil bag with a zip seal, 5kg double sealed box and a 25kg fibre drum with polyethylene liner. All packages come with desiccant and oxygen absorber packets to keep enzyme activity throughout shipping.

Samples and small orders are shipped via DHL, FedEx and UPS express services. Bulk goods are sent via air freight or consolidated sea container depending on the necessity. For speedier regional distribution we have strategic warehouse agreements in California and Rotterdam.

The standard shipping period is 1-3 working days for items in stock after the payment has been verified. 15-20 days for production and checking quality for custom specs. All shipments come with temperature monitoring data and comprehensive customs documentation for your import compliance.

Why Choose Us?

10 Years Of Natural Ingredient Expertise: Yanxi Biotech has been devoted to the extraction of enzymes and the production of botanical ingredients since 2010. Our fermentation engineers have decades of combined experience in Bacillus subtilis culture optimisation for optimal nattokinase production.

Integrated manufacturing Control: We handle all of the manufacturing variables from the purchase of raw material to final packaging. This vertical integration removes third-party quality risk and reduces lead time by 30% over brokers.

Global Export Experience: We sell our products in 100+ countries and have received regulatory approval in North America, European Union, Australia and Asia-Pacific markets. We understand regional compliance needs and can provide country specific paperwork bundles.

Responsive Technical Support: Our applications team can help with formulation issues, stability study design and label claim support. The product development cycle provides direct access to PhD food scientists and regulatory specialists.

Competitive Pricing Structure: Factory-direct sourcing eliminates distributor markups. Volume commitments include tiered pricing discounts and specific production slots. You are operating within your financial limitations and uncompromising quality standards are upheld.

FAQ

Q: What is the odor characteristic of this powder?

A: Our purified product undergoes specialized odor removal processing. The final product exhibits minimal aroma, making it ideal for encapsulation without requiring masking agents or flavoring systems.

Q: What are the main application fields?

A: This enzyme powder serves cardiovascular supplement manufacturers, functional food developers, and pharmaceutical researchers. Primary applications include blood health capsules, circulation support tablets, and clinical research formulations.

Q: Can it withstand high-temperature processing?

A: Yes, our stabilized enzyme maintains activity through 90℃ processing for 15 minutes. This heat tolerance supports hot-fill encapsulation, tableting compression, and pasteurization processes common in commercial production.

Q: What is the carbohydrate content?

A: The powder contains 50-60% carbohydrate content, primarily consisting of insoluble polysaccharides from the fermentation substrate. These compounds provide additional cholesterol management benefits and improve powder flowability.

Q: Do you provide samples for testing?

A: We offer free 50-100g samples for qualified buyers to conduct formulation trials and analytical verification. Sample requests ship within 24 hours via express courier with full COA documentation.

Contact Us for Professional Cardiovascular Ingredient Solutions

Ready to enhance your product formulations with Nattokinase Powder? Contact our technical team at info@yanxiherbs.com for pricing quotations, technical data sheets, and custom specification inquiries.