Dihydromyricetin Powder for Functional Beverage Development
Nov 02, 2026
Dihydromyricetin Powder is a plant-derived flavonoid ingredient that beverage brands use to build liver-support and hangover relief drinks. We extract it from vine tea (Ampelopsis grossedentata), and our 98% grade comes as a light yellow powder with a fine particle size that disperses in water. Successful development depends on three things: verified purity, a formula that handles limited cold-water solubility, and compliant labeling for the U.S. market. This guide covers each step, from how the ingredient works to how to source it in bulk, so your R&D, purchasing, and quality teams can decide with confidence.
Understanding Dihydromyricetin Powder and Its Role in Functional Beverages
What the Ingredient Is and Where It Comes From
Flavonoids include flavonols. It's also known as DHM or ampelopsin. A thick plant called Ampelopsis grossedentata brings in most of the money. People in southern China have made vine tea with the leaves for a long time. The compound is taken out and cleaned up by the company that makes it. It is a light yellow Dihydromyricetin Powder that is 98% pure. A review of studies that looked at its effects on metabolism, inflammation, and antioxidants came out in 2018 in Frontiers in Pharmacology. DHM comes from a leaf of a plant that was once used to make tea. Because of this, it fits with the story that many drink brands want to tell about being plant-based and green.
How It Works: Alcohol Metabolism and Antioxidant Activity
DHM is interesting to many people because it has been used to study drinking. The study, which came out in 2012 in The Journal of Neuroscience, found that DHM seemed to work on GABA-A receptors in the brain and made rats less obviously drunk after drinking. A 2020 study in the journal Clinical and Experimental Research found that DHM changed how lipids and ethanol were broken down in mice. DHM could be good for the liver because of this. In other research, DHM has been connected to ADH and ALDH. These are the enzymes that work to break down alcohol. I want to know the rules. We should stick to low claims for products that are based on what we know from cell and animal models.
Why Beverage Brands Are Adding It
These days, people who drink with friends look for healthy ingredients. DHM is mostly found in shots that are good for your liver and drinks that help with hangovers. This works with the small, light yellow Yanxi Herbs 98% powder that you can mix with water. When people buy something, they each get something different. It is clear what needs to be done for research and development, and the norm is stable. You get something in stock and in a clear pack size when you buy something. Getting certificates and transferring data to a file is part of being good. One chemical can help protect the liver, ease pain, and fight free radicals as long as the label says how it works.
Quality and Effectiveness: Choosing the Right Dihydromyricetin Powder
Purity and Specification Checks
This is what you need to know about our Dihydromyricetin Powder:
- The main element is Dihydromyricetin;
- It is 98% pure;
- Appearance: Light yellow powder;
- Particle size: All particles are the right size to fit through 80 mesh;
- Loss after drying: ≤5%;
- Ash content: 5%;
- Heavy metals: 10 parts per million;
- Total plate count: <1000 cfu/g;
- Yeast and mold count: <100 cfu/g;
- Shelf life: It will last for 24 months if it is sealed and stored properly.
Things can still be spread out even when they are small. Your quality team can easily check the goods when they arrive thanks to the limits for ash, wetness, heavy metals, and bacteria. A lot of people who want to sell their goods in the U.S. and other countries look for things that are approved by ISO, HACCP, FDA, Kosher, and Halal.
Natural Extract Versus Synthetic Sources
Vine tea is taken out of the plant naturally and then ground into a powder. Chemicals are not used to make it. That source is important for clean-label brands because it shows up on the label and in checks that look at where the food comes from. Ask the seller to name the plant material and explain how it was taken out of the plant. Also, look to see if any Dihydromyricetin that was not made naturally is mixed in. An HPLC test can tell you how much Dihydromyricetin is in the powder. If you think there has been fraud, a C14 radiocarbon test can tell the difference between carbon that comes from trees and carbon that comes from oil. This isn't the only thing you can give your quality team to check. There can be a 98% test, a clean chromatogram, and a record of each batch.
How It Compares With Milk Thistle and Green Tea Extract
A lot of people who want to buy DHM say it tastes like a mix of milk thistle and green tea strain. To keep the liver healthy, silymarin from milk thistle has been used for a long time. Its main job is to keep liver cells safe. It looks at DHM from a different point of view, like how alcohol is broken down and how it impacts the brain. This is one of the catechins that is found in green tea extract. Most people respect these for their antioxidant and digestive benefits. These parts work together to help the liver in some ways, but they are not the same thing. Some brands put them together to make the story of the product longer. If you want to go out at night, DHM is a better choice. To keep the liver healthy every day, green tea extract, silymarin, or a mix of the two might work better. You can pick by style, claim, or customer.
Formulation Guide: How to Add Dihydromyricetin Powder to Functional Beverages
Dosage Planning
How much you use hinges on the goods and the point you want to make. On the market, most items have 100 mg to 600 mg of Dihydromyricetin Powder in each dose. These are usually taken before or after drinking. Pharmacological Research published a study in 2015 that looked at people with nonalcoholic fatty liver disease. They were given 150 mg twice a day for three months. They said it improved the way glucose and fats were broken down and decreased inflammation. That study wasn't about hangovers; it was about liver disease. I believe your R&D team should begin with a medium-sized dish, test it, and then make changes only after confirming that it stays stable. To find the active amount, you should use the 98% assay instead of the powder's weight.
Solving Solubility and Stability
The main trouble with the tech is that it can't be fixed. DHM and cold water don't mix as well as hot ethanol and water do. Air, light, and heat can all break down flavonoids. Our powder is very fine—everything fits through an 80-mesh sieve—so it's easy to mix with water. The powder should stay in clear, ready-to-drink drinks, but it should also settle down. To stop sedimentation, you could use complexes that dissolve or mix well, like gamma-cyclodextrin. No need to worry about these things when you drink dry drink mixes and clear drinks. If the pH level goes up, antioxidants often become less stable, so you should check it. Also, keep drinks out of light. Before getting big, try the longer shelf life on small amounts.
U.S. Labeling and Claims
If an item is sold in the US as either a vitamin or a regular drink, the rules for labeling change. Why is this? The Dietary Supplement Health and Education Act of 1994 says so. Some of the things that food product makers can say are "supporting liver health." If they put it on the market, they have to tell the FDA about it within 30 days. They have to include the usual notice that the FDA has not looked over the statement. You shouldn't say that something can help someone get better. People who make supplements must also follow the rules in 21 CFR Part 111 in order to do it right. So you should talk to a professional before you start because the way an item is packed can change how it is controlled. To help you with that review, we give you specs, certificates, and batches of documents.
Procurement and Supply Chain: Sourcing High-Quality Dihydromyricetin Powder
Bulk Buying and Cost Planning
Buying a lot at once is better. Get a free sample of your base to check out how it looks, tastes, and spreads. For test runs, switch to a 1 kg bag or 5 kg box. You need to order 25 kg drums of everything. In stock, we have Dihydromyricetin Powder. It will be sent out one to three business days after we get paid. This helps plan things more quickly. The prices change based on the goods' costs and the number of orders. You can compare quotes for different order sizes to what you think will happen. When you buy small things, you don't have to be in a hurry if you know they will last 24 months if you store them right and cover them. When you help local shops in both Europe and the US, service is faster for people in the US as well.
How to Evaluate a Supplier
Before you give a supplier the go-ahead, do these three things.
- Documentation: When you ask for an analysis certificate for each batch, make sure it has information about the assay, a heavy metal count, and an HPLC result. Check that each value matches the agreed-upon value, and make sure the supplier gives you these files before the shipment. Paperwork that is quick and easy to understand is often a sign of good quality control.
- Certifications: If the seller says they have up-to-date ISO, HACCP, Kosher, and Halal certificates, make sure they do and ask for copies. Also, check to see if the source is FDA-registered. Keep in mind that FDA registration only means that the building has signed up with the FDA. This doesn't mean that the FDA agreed with the drug or any of the things that were said about the product.
- Help and support: Check the wait times, package options, and availability of the service before making your choice. The powder will be sent to you in one to three business days after you pay. There are 25 kg drums, 5 kg boxes, and 1 kg bags of it. Ask the seller how they handle return customers, unique requests, and technical questions from your R&D team.
Logistics and Compliance for U.S. Imports
Yanxi Biotech's Yanxi Herbs has been making and sending natural products to more than 100 countries and regions since 2010. For stores in the US and Europe, we help get things ready to send abroad. If someone from the U.S. wants to bring goods into the country, they should also check the FDA's rules on imports, like the Prior Notice for Food Shipments and the Foreign Supplier Verification Program duties, to see if they apply. Place the powder somewhere cool, dry, and out of the light. Also, keep it in the drums it came in or in double-layer plastic bags to keep it from going bad. If you have clear shipping terms, the right customs paperwork, and one person to talk to, your factory won't have to wait for a package that's been delayed.
Conclusion
In order to make functional drink names sound more plant-based, Dihydromyricetin Powder is made from vine tea. Most of the proof for these chemicals' ability to help break down alcohol, protect the liver, and fight free radicals comes from studies on animals. A 98% test, clear instructions, batch records, and tests that show the product comes from natural sources are the first things that make something good. It's hard to make them because they don't mix well with cold water, and light and heat can damage them quickly. Test them first and choose the right drink style to fix these problems. The amounts on the market are between 100 mg and 600 mg, and U.S. labels have to follow DSHEA rules. There is a steady supply, and people buy things by following the rules. Stock availability, staged orders, and the right import paperwork are used to make this happen.
FAQ
What dosage should I use in a beverage?
There are many things you can buy that have 100 mg to 600 mg of Dihydromyricetin in each dose. In a 2015 study, 150 mg was taken twice a day. Pick your level based on the style, the claim, and what the government says.
How do I verify the purity of the powder?
Ask for a batch proof of analysis that has been tested with an HPLC. After that, check to see if the levels of germs and heavy metals are right. Ask for a C14 radiocarbon test if you think the food was changed in a lab.
Does the powder dissolve in cold drinks?
That stuff called Dihydromyricetin breaks down better when the water is warm. We need to do the bench tests to make sure the cold drinks are clear. It's easy to mix our fine 98% powder with water. It's possible to warm the mix up or use gamma-cyclodextrin complexes.
Is the powder natural or synthetic?
From vine tea (Ampelopsis grossedentata), our powder comes. If you store it and pack it right, it will last for 24 months.
Request Dihydromyricetin Powder Samples and Quotes From Yanxi Herbs
You can buy 98% pure Dihydromyricetin Powder from Yanxi Herbs. They ship it out 1–3 business days after you pay. They let people try things for free. Email us at info@yanxiherbs.com with the type of drink you want, how much you need each month, and any paperwork you need. We'll get back to you with a price and an information sheet. Just go to yanxiherbs.com to learn more.
References
1. Shen Y, et al. Dihydromyricetin as a novel anti-alcohol intoxication medication. The Journal of Neuroscience, 2012.
2. Silva J, et al. Dihydromyricetin protects the liver via changes in lipid metabolism and enhanced ethanol metabolism. Alcoholism: Clinical and Experimental Research, 2020.
3. Chen S, et al. Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: a randomized controlled trial. Pharmacological Research, 2015.
4. Zhang J, et al. Recent update on the pharmacological effects and mechanisms of dihydromyricetin. Frontiers in Pharmacology, 2018.
5. U.S. Food and Drug Administration. Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements (21 CFR Part 111), 2007.
6. U.S. Congress. Dietary Supplement Health and Education Act, 1994.
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